Setbacks on the Path to CAR T Cell Therapy Approval

Setbacks on the Path to CAR T Cell Therapy Approval

Many scientists, physicians, and patients are looking to immuno-oncology as the future of cancer treatment, especially with cutting-edge immunotherapeutic techniques like chimeric antigen receptor (CAR) T cell therapy, which has been called a “living drug.” This phrase refers to the fact that the therapy is derived from the patient’s own living cells. The treatment begins… Read More…

How Does Your Immune System Protect You?

How Does Your Immune System Protect You?

In recent years, immuno-oncology has received a lot of hype and praise because of some high-profile success cases, such as former president Jimmy Carter, and investments from popular culture icons like Sean Parker. What makes immunotherapy such an exciting option for the field of oncology is that it bolsters the body’s natural immunity to disease.… Read More…

Amazing New Drug Shows Strong Promise for Multiple Tumor Types

Amazing New Drug Shows Strong Promise for Multiple Tumor Types

Recently, BeiGene presented the preliminary findings of an ongoing dose-escalation Phase I study of BGB-A317, a checkpoint inhibitor. The presentation was made at the 2016 Annual Meeting of the American Society of Clinical Oncology in Chicago. BGB-A317, a monoclonal antibody, is designed to bind to PD-1, a receptor on the surface of cells that downregulates… Read More…

What You Need to Know about Cytokines in Immuno-Oncology

What You Need to Know about Cytokines in Immuno-Oncology

One of the main approaches to cancer immunotherapy involves cytokines, which serve as messengers for the immune system. Immune cells secrete cytokines, which are proteins or glycoproteins, to strengthen or suppress normal immune functions. Researchers are attempting to take advantage of this regulatory role to boost the activity of macrophages and natural killer cells, as… Read More…

Immuno-Oncology Research: The Need to Stand Out in the Crowd

Immuno-Oncology Research: The Need to Stand Out in the Crowd

Immuno-oncology has become a central focus for medical research firms and organizations across the country, and many are working on the same targets. Over the past five years, interest in immuno-oncology has spiked dramatically due to real changes in survival curves for many cancers and the extraordinary amount of money being made available. While all… Read More…

CAR T-Cell Therapy: Engineering Your Immune Cells to Fight Cancer

CAR T-Cell Therapy: Engineering Your Immune Cells to Fight Cancer

One of the most important questions that immuno-oncologists will tackle in the coming years is figuring out where chimeric antigen receptor (CAR) T-cell therapy will fit into the larger picture. Academic centers across the country have been using this technology to successfully treat patients, but adapting this complicated system to a community setting introduces a… Read More…

A Look at the Role Monoclonal Antibodies Play in Immuno-Oncology

A Look at the Role Monoclonal Antibodies Play in Immuno-Oncology

Immuno-oncological research is exploring several different approaches to immunotherapy, including vaccines, checkpoint inhibitors, and monoclonal antibodies. At present, several different types of monoclonal antibody drugs exist, but researchers are still exploring how to employ them most effectively in a treatment plan. The term monoclonal antibody refers to a molecule produced in a laboratory that has… Read More…

A Brief Look at the History of Immuno-Oncology

A Brief Look at the History of Immuno-Oncology

In recent years, advances in immuno-oncology have generated a lot of excitement about the future of cancer care. From radical new therapies to combinations with existing approaches, the field is generating a remarkable amount of hope. While the future looks bright, it is important to understand and revisit the history of immuno-oncology, which dates back… Read More…