Category Archives: Cancer

2 of the New Studies That Suggest the Benefits of Cancer Immunotherapy

2 of the New Studies That Suggest the Benefits of Cancer Immunotherapy

As new immuno-oncology therapies emerge, they are proving effective against an increasingly wide range of cancers. Importantly, immunotherapies have proven effective in treating previously intractable tumors and rare cancers. The results of continued research increasingly place immuno-oncology at the heart of new anti-cancer tactics. As researchers redouble their efforts to understand what makes the immune… Read More…

We Need Better Ways to Judge Cancer Immunotherapy’s Efficacy

We Need Better Ways to Judge Cancer Immunotherapy’s Efficacy

A report in the November 1, 2015, issue of the Journal of Clinical Oncology, “Pseudoprogression and Immune-Related Response in Solid Tumors,” raised important questions about measuring the efficacy of immunotherapy in the treatment of cancer. Immuno-oncology has become a major field of research, and scientists are applying immunotherapy to the treatment of many cancers. However,… Read More…

New Clinical Trials Explore Cancer Immunotherapy Combinations

New Clinical Trials Explore Cancer Immunotherapy Combinations

As competition in the immuno-oncology field continues to ramp up, a number of biotech and pharma startups, as well as established companies, are leaping for the chance at a big payoff and an effective new cancer therapy attached to their name. Recently, oncology-focused firm TESARO, based in Waltham, Massachusetts, announced that it has commenced a… Read More…

A New Patch Delivers Immunotherapy Directly to Melanoma Tumors

A New Patch Delivers Immunotherapy Directly to Melanoma Tumors

One of the primary focuses in immuno-oncology is how to deliver treatments to make them most effective. Research on these delivery mechanisms ranges from biological markers and personalized medicine to mechanical methods. While immunotherapy has proven especially effective for some patients, others may see little or no benefit, which has spurred researchers to figure out… Read More…

Johns Hopkins Opens New Cancer Immunotherapy Institute

Johns Hopkins Opens New Cancer Immunotherapy Institute

A number of exciting programs at leading companies and research institutions have emerged exploring the potential of immuno-oncology. In March, Johns Hopkins University in Baltimore announced the inception of its Bloomberg-Kimmel Institute for Cancer Immunotherapy, which purportedly embraces the “moonshot” of the Obama administration to cure cancer. The center is funded by two $50 million… Read More…

Immuno-Oncology – What Do People Want to Know?

Immuno-Oncology – What Do People Want to Know?

Cancer immunotherapy is a field that has seen remarkable growth in the past decade. This growth is largely driven by some incredible stories of success. While immuno-oncology’s potential to provide treatments for even the most intractable cancers is high, a number of questions still exist, from exactly how to apply insights in the clinical setting… Read More…

Provenge Honored as First FDA-Approved Cancer Vaccine

Provenge Honored as First FDA-Approved Cancer Vaccine

One of the most prominent approaches to immuno-oncology involves the development of cancer vaccines. While people may be familiar with vaccines that help prevent disease, much immuno-oncological research is focusing on how vaccines can optimize the immune response to specific tumors. Several preventative vaccines for cancer do exist, such as options for preventing human papillomavirus… Read More…

Spotlight: Tumor-Specific T Cells Found in Circulating Blood

Spotlight: Tumor-Specific T Cells Found in Circulating Blood

One of the most promising avenues of research in terms of targeted immuno-oncology is targeting the neoantigens expressed by mutated DNA in cancer tumors. Researchers have demonstrated that human T cells have the ability to recognize and destroy tumor cells—a fact that has spurred the current interest in immunotherapy. Specifically, T cells use clone-specific T… Read More…

How Are Vaccines Being Applied to the Treatment of Cancer?

How Are Vaccines Being Applied to the Treatment of Cancer?

Some immuno-oncology therapies that have shown potential for clinical applications and that have already received approval from the Food & Drug Administration (FDA) are cancer vaccines. In general, vaccinations are used to train the body to fight disease. In the field of cancer, researchers have focused on two different types of vaccines: preventive and therapeutic:… Read More…

A Look at the Immune Response to Cancer and Checkpoint Inhibitors

A Look at the Immune Response to Cancer and Checkpoint Inhibitors

With targeted immuno-oncology therapies showing promise in clinical trials, competition has increased among biotech firms to bring products to the market. One approach to immuno-oncology treatment that is becoming more popular involves checkpoint inhibitors. In fact, the surge in research on certain regulatory checkpoints has helped to reinvigorate the field of immuno-oncology in recent years.… Read More…